Abstract Carbapenem-resistance in Klebsiella pneumoniae (KP) sequence type ST258 is mediated by carbapenemases (e.g.KPC-2) and loss or modification of the major Vinyl 6" 78 non-selective porins OmpK35 and OmpK36.However, the mechanism underpinning OmpK36-mediated resistance and consequences of these changes on pathogenicity remain unknown.By solvin
Molecular structure, electronic, topology and non-covalent interaction of 4-(Bis(2-chloroethyl)amino)-L-phenylalanine- Anti-blood cancer activity
In this study, it is attempted to scrutinize the global minimum energy structure of anti-blood cancer drug 4-(Bis(2-chloroethyl)amino)-L-phenylalanine (4B2CA-LPA) and functionalized density functional theory (DFT) calculations regarding their GINGER ROOT 1200MG geometries, topological features of covalent, non-covalent interactions with employing A
Problems of the Welfare State as an Employer: Assuring the Availability and Commitment of Street-Level Bureaucrats. A Literature Review
Among the important trends in Western welfare states in recent decades, there is an increasing reliance on services.With services being irreducibly labor-intensive, this trend has put social workers, health and care workers, legal advisors, and other professional groups at the center stage.Only if the welfare state can attract enough qualified work
Improve Ship Propeller Efficiency via Optimum Design of Propeller Boss Cap Fins
This paper aims to cost-effectively improve the energy efficiency of large vessels in shipping by the optimum design of propeller boss cap fins (PBCFs).First, a model propeller of the modern four-blade propeller in a Ro-Ro ship, with no boss cap fin in its original design, is experimentally and numerically investigated.The computational fluid dynam